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The History of Biomedical Research
In the 1900's to the 1920's, Animal Research Was Essential in the Following Developments:
- Discovery of thyroxin, adrenaline, acetylcholine
- Discovery and therapeutic use of insulin
- Development of a technique for freeze-drying tissues
- Development of antitoxin for scarlet fever
Nobel Prizes in Medicine Which Involved Animal Models:
|
Year |
Scientist/s |
Animal/s Used |
Contribution Made |
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| 1901 |
von Behring |
Guinea pig |
Development of diphtheria antiserum |
| 1902 |
Ross |
Pigeon |
Understanding of malaria life cycle |
| 1904 |
Pavlov |
Dog |
Animal responses to conditioning and gastric
functioning. |
| 1905 |
Koch |
Cow, Sheep |
Studies of pathogenesis of tuberculosis |
| 1906 |
Golgi, Cajal |
Dog, Horse |
Characterization of the central nervous system |
| 1907 |
Laveran |
Bird |
Role of protozoa as cause of disease |
| 1908 |
Metchnikov, Ehrlich |
Bird, fish, guinea pig |
Immune reactions and functions of phagocytes |
| 1910 |
Kossel |
Bird |
Knowledge of cell chemistry through work on proteins
including nuclear substances |
| 1912 |
Carrel |
Dog |
Surgical advances in the suture and grafting of
blood vessels |
| 1913 |
Richet |
Dog, Rabbit |
Mechanisms of anaphylaxis |
| 1919 |
Bordet |
Guinea pig, horse, rabbit |
Mechanisms of immunity |
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