The History of Biomedical Research

 

 

In the 1940's, Animal Research Was Essential in the Following Developments:

  • Treatment of rheumatoid arthritis
  • Therapeutic use of streptomycin
  • Discovery of the Rh factor in blood
  • Prevention of diphtheria
  • Eradication of cattle tick fever
  • Treatment of whooping cough
  • Therapeutic use of antibiotics (penicillin)
  • First successes in kidney and skin transplantation

Nobel Prizes in Medicine Which Involved Animal Models:

 

Year Scientist/s Animal/s Used Contribution Made
       
1943 Dam, Doisy Rat, dog, chick, mouse Discovery of function of vitamin K
1944 Erlanger, Gasser Cat Specific functions of nerve cells
1945 Fleming, Chain, Florey Mouse Curative effect of penicillin in bacterial infections
1947 Carl Cori, Gerty, Cori, Houssay Frog, toad, dog Catalytic conversion glycogen; role of pituitary in sugar metabolism
1949 Hess, Moniz Cat Functional organization of the brain as a coordinator of internal organs