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The History of Biomedical Research
In the 1970's, Animal Research Was Essential in the Following Developments:
- Discovery of cimetidine for ulcers
- Treatment for leprosy
- Development of hepatitis B vaccine
- Advances in cardiology (measuring of coronary blood flow; myocardial preservation; heart transplant refined; coronary bypass surgery)
- Prevention of measles
- Identification of feline leukemia virus
- Eradication of Venezuelan equine encephalitis and hog cholera
- Discovery of the link between cholesterol and heart disease
Nobel Prizes in Medicine Which Involved Animal Models:
|
Year |
Scientist/s |
Animal/s Used |
Contribution Made |
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| 1970 |
Katz, von Euler, Axelrod |
Cat, Rat |
Mechanisms of storage and release of nerve
transmitters. |
| 1971 |
Sutherland |
Rat |
Mechanism of the actions of hormones |
| 1972 |
Edelman, Porter |
Guinea Pig,
Rabbit |
Chemical structure and nature of antibodies |
| 1973 |
von Frisch, Lorenz, Tinbergen |
Bird, Bee |
Organization of social and individual behavior
patterns in animals. |
| 1974 |
de Duve, Palade, Claude |
Chicken,
Guinea Pig, Rat |
Structural and functional organization of cells |
| 1975 |
Baltimore, Dulbecco, Temin |
Monkey, horse, chicken, mouse |
Interaction between tumor viruses and genetic
material. |
| 1976 |
Blumberg, Gajdusek |
Chimpanzee |
Slow viruses and new mechanism for dissemination of
diseases. |
| 1977 |
Guiltemin, Schally, Yalow |
Sheep, pig |
Role of hypothalamic hormones in the body |
| 1979 |
Cormack, Hounsfield |
Pig |
Development of computer-assisted tomography (CAT
scan) |
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