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The History of Biomedical Research
In the 1980's, Animal Research Was Essential in the Following Developments:
- Development of monoclonal antibodies for treating diseases
- Research on communicative abilities (leading to strategies for teaching children with mental disabilities)
- Discovery of genetic factors leading to treatments for predisposition to such disorders as chronic anxiety
- Understanding of viral function in AIDS, Alzheimer's Disease and other degenerative disorders
- First stages of development of gene therapy / replacement
- Therapeutic use of cyclosporin
- First human intrauterine surgery
- Discovery of prostaglandin
Nobel Prizes in Medicine Which Involved Animal Models:
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Year |
Scientist/s |
Animal/s Used |
Contribution Made |
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| 1980 |
Benacerraf, Dausset, Snel |
Mouse, Guinea Pig |
Identification of histocompatibility antigens and
mechanism of action |
| 1981 |
Sperry, Hubel, Wiese |
Cat, Monkey |
Processing of visual information by the brain |
| 1982 |
Bergstrom, Samuelsson, Vane |
Rat, Rabbit, Guinea Pig |
Discovery of prostaglandin's |
| 1984 |
Milstein, Kohler, Jerne |
Mouse |
Technique of monoclonal antibody formation |
| 1986 |
Levi-Montalcini, Cohen |
Mouse, chick, snake |
Nerve growth factor and epidermal growth factor |
| 1987 |
Tonegawa |
Mouse embryo |
Basic principles of antibody synthesis |
| 1989 |
Varmus, Bishop |
Chicken |
Cellular origin of retroviral oncogenes. |
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