African clawed frogs are also used in research. They have long been used by
developmental biologists to study various aspects of the early development of
organisms.
Magainins are a remarkable family of antibiotics first isolated from the skin
of these frogs. These peptides, which facilitate wound healing, are the key to
the frogs' set of defenses against disease.
Apparently more versatile than other classes of antibiotics, magainins are active
in the test tube against many types of bacteria, as well as fungi, protozoa and some
viruses.
Some research also suggests that magainins may kill certain kinds of cancer cells.
Magainins have been shown to be present in mice and humans as well.
Since these peptides appear to be active against protozoa, including the kinds that
cause malaria, this work has important implications for tropical countries,
where malaria is a major cause of human and animal deaths.