History of Biomedical Research - 1920's

Animal Research Was Essential in the Following Developments:

• Discovery of thyroxin, adrenaline, acetylcholine
• Discovery and therapeutic use of insulin
• Development of a technique for freeze-drying tissues
• Development of antitoxin for scarlet fever

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Nobel Prizes in Medicine Which Involved Animal Models:

Year	Scientist/s	Animal/s Used	Contribution Made
1920	Krogh	Frog	Discovery of capillary motor regulating system
1922	Hill	Frog	Consumption of oxygen and lactic acid metabolism in muscle
1923	Banting, Macleod	Dog, rabbit, fish	Discovery of insulin and mechanism of diabetes
1924	Einthoven	Dog	Mechanism of the electrocardiograph
1928	Nicolle	Monkey, pig, rat, mouse	Pathogenesis of typhus
1929	Eijkman, Hopkins	Chicken	Discovery of antineuritic and growth stimulating vitamins