History of Biomedical Research - 1960's

Animal Research Was Essential in the Following Developments:

• Prevention of rubella
• Development of lithium
• Advances in heartworm prevention and canine distemper vaccine
• Development of antipsychotic and antidepressant drugs
• First human liver, single lung, pancreas, heart, corneal and heart/lung transplants

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Nobel Prizes in Medicine Which Involved Animal Models:

Year	Scientist/s	Animal/s Used	Contribution Made
1960	Burnet, Medawar	Rabbit, Mouse	Understanding of acquired immune tolerance
1961	von Bekesy	Guinea Pig	Physical mechanism of stimulation in cochlea
1963	Eccles, Hodgkin, Huxley	Cat, Frog, squid, crab	Ionic involvement in excitation and inhibition in peripheral and central parts of nerve cells
1964	Bloch, Lynen	Rat	Regulation of cholesterol and fatty acid metabolism
1966	Rous, Huggins	Rat, rabbit, hen, dog	Tumor-inducing viruses and hormonal treatment of cancer.
1967	Hartline, Granit, Wald	Chicken, rabbit, fish, crab	Primary physiological and chemical processes of vision
1968	Holley, Khorana, Nirenberg	Rat	Interpretation of genetic code and its role in protein synthesis